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Iron deficiency without anaemia: when the blood count is normal

“Your blood count is normal” – and yet the iron stores are empty. This happens because haemoglobin only falls late. Why it is especially common in women and which value shows it.

Updated: September 2026

Also in: Deutsch · Español

Stores empty, blood count normal

Iron deficiency particularly affects women before menopause. Anaemia is only one of its consequences; impairments can occur before the blood count becomes abnormal. That is how a 2021 review in The Lancet sums it up.

Which value shows it

Ferritin shows how full the stores are. Exactly where the threshold lies is debated. A 2021 study of more than 1,000 young women measured when the body starts absorbing more iron from food: as soon as ferritin falls below about 50 µg/l. The authors interpret this as the beginning of iron deficiency. Other thresholds are set lower – ask which threshold your lab uses and where your value lies.

There is more for athletes in our article on iron, periods and sport (in German).

The most common cause: periods

Periods mean losing iron; that is why the German Nutrition Society recommends 16 mg a day for women before menopause, compared with 11 mg for men. Heavy menstrual bleeding is one of the most important reasons for iron deficiency and is often not taken seriously. How to recognise it is explained in our article on heavy periods.

The Lancet review stresses that the cause should always be looked for; considering a test for coeliac disease is part of this routinely.

Treat – but based on test results

In most cases the first choice is iron taken by mouth. High doses are absorbed less well because the body then reduces absorption. The amount is for your doctor to decide; Rhythmus deliberately gives none.

An analysis of 21 studies from 2022 found that in iron deficiency without anaemia, iron given as an infusion slightly improved physical performance and slightly reduced tiredness. The quality of the evidence was mostly low; quality of life did not differ.

Sources

  1. Pasricha, S.-R., Tye-Din, J., Muckenthaler, M. U. & Swinkels, D. W. (2021): Iron deficiency. The Lancet 397(10270), 233–248. View source
  2. Galetti, V., Stoffel, N. U., Sieber, C. et al. (2021): Threshold ferritin and hepcidin concentrations indicating early iron deficiency in young women based on upregulation of iron absorption. EClinicalMedicine 39, 101052. View source
  3. Munro, M. G., Mast, A. E., Powers, J. M. et al. (2023): The relationship between heavy menstrual bleeding, iron deficiency, and iron deficiency anemia. American Journal of Obstetrics & Gynecology 229(1), 1–9. View source
  4. Dugan, C., Cabolis, K., Miles, L. F. et al. (2022): Systematic review and meta-analysis of intravenous iron therapy for adults with non-anaemic iron deficiency: An abridged Cochrane review. Journal of Cachexia, Sarcopenia and Muscle 13(6), 2637–2649. View source
  5. Deutsche Gesellschaft für Ernährung (Ableitung 2023): Referenzwerte für die Nährstoffzufuhr: Eisen. DGE. View source

The complete list of sources is in the app under Help & FAQ.

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